Endocrine Abstracts

It is suggested that estrogen hormones involve pathways controlling histone acetylation to brought about their effects in the uterus. However, it is not known how the level of histone acetylation affect estrogen-dependent processes in the uterus, especially proliferation and morphogenetic changes. Therefore, effects of histone deacetylase blockers, trichostatin A and sodium butyrate, on proliferative and morphogenetic reactions in the uterus under long-term estrogen treatment ...

Retrospective randomized blinded study was carried out to find differences in hormone levels in blood between groups of patients with normal endometrium and with endometrial benign hyperplastic lesions. Hospital cases were randomly selected from journals of admittance from 1997 to 2005 years. Only patient name, age and clinical diagnosis, in which endometrial histology was reflected, could be viewed at the time of cases selection. There were to groups of cases selected, with a...